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IL-12A Polyclonal Antibody, 100ul Bottle-Top Dispenser It forms a homodimer or

SKU: 46846066728

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IL-12A Polyclonal Antibody, 100ul Bottle-Top Dispenser It forms a homodimer orIL12A encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide linked heterodimer composed of the 35 kD subunit encoded by this gene, and a 40 kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T cell independent induction of interferon (IFN) gamma, and is important for the differentiation of both Th1 and Th2 cells.

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Description

It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription

multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane

The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas

The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane

but another polymorphism has been associated with increased plasma cholesterol levels

IL-12A Polyclonal Antibody, 100ul Bottle-Top Dispenser It forms a homodimer orIL12A encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide linked heterodimer composed of the 35 kD subunit encoded by this gene, and a 40 kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T cell independent induction of interferon (IFN) gamma, and is important for the differentiation of both Th1 and Th2 cells.

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